Abstract
A 52-year-old man was referred to our hospital for further investigation and treatment of a tumor shadow noted on chest X-ray in January, 2000. The chest CT scan showed a large tumor shadow in the right upper lobe. Tumor markers (keratin, SLX, CYFRA and NSE) were elevated. On January 25, right upper lobectomy with regional lymph node dissection and partial resection of the third rib were performed . Pathological diagnosis was combined large cell neuroendocrine carcinoma (LCNEC) and squamous cell carcinoma, and histological staging grade was II B (T3N0M0). The postoperative course of the patient was good, but he had a local recurrence 10 months after discharge and then died.
