Abstract
A 46-year-old woman with three episodes of right pneumothorax related to onset of menstruation was reported. Video-assisted thoracoscopic surgery (VATS) revealed the presence of some defects in the central tendon of the diaphragm. Partial resection of the diaphragm including the lesions was performed. Histological findings of the resected diaphragm were compatible with catamenial pneumothorax. Leuprorelin as hormonal therapy was administered for 8 months post surgically. Seven months after cessation of the hormonal therapy, right pneumothorax relapsed. Hormonal therapy is necessary for prevention of relapse after VATS of catamenial pneumothorax.