Abstract
A 73-year-old man was referred to our hospital with bilateral foot edema and severe gonalgia. His chest X-ray film showed an abnormal shadow in the right lower lobe. The histological diagnosis of tissue obtained by bronchoscopy was large cell carcinoma. Bone scintigraphy showed abnormal linear accumulation along the cortical margin of the femur. His fingers and toes were clubbed and his nails were thickened and white. Those scrapings showed trichophiton. His serum level of FSH was slightly high but LH, PTH, estrogen and calcitonin were normal. Foot edema disappeared within a week after lobectomy, and gonalgia was greatly reduced. Tinea unguium improved steadily. This is the first case of hypertrophic pulmonary osteoarthropathy to be reported in which tinea unguium was spontaneously cured after resection of lung cancer with no use of antifungal agents.