Abstract
Leukocytoapheresis (LCAP) is a treatment that reduces the production of cytokines by removing activated leukocytes from both peripheral blood and local inflamed lesions. LCAP has been reported to be is effective for the treatment of inflammatory bowel diseases and rheumatoid arthritis. We treated four patients with LCAP who were suffering from multiple organ failure as a result of sepsis. LCAP improved their pulmonary function and circulation status, but did not contribute to saving their lives. To prevent a second attack on major organs and to save patients with multiple organ failure, LCAP may be used during early sepsis.
