Abstract
We analyzed the severity grade according to the guidelines for acute cholecystitis (AC), and compared the domestic guidelines with the Tokyo guidelines. Two hundred thirty-three AC patients who underwent cholecystectomy were enrolled. The AC severity grade according to the domestic guidelines was classified as Mild 20. 2%, Moderate 46.8%, and Severe 33.0%, while according to the Tokyo guidelines it was classified as Mild 42.1%, Moderate 57.1%, and Severe 0.8%. In the analysis of each set of guidelines, appropriate classification was demonstrated from the point of view regarding inflammatory findings. However, in comparison between the Mild and Moderate classifications in both guidelines, there was a significant difference in the inflammatory findings. The severity grade in the Tokyo guidelines showed more significant inflammation than the domestic guidelines. Therefore, large population-based studies related to the guidelines, especially the Tokyo guidelines are required to ascertain the outcomes depend on the severity grade. Furthermore, it was felt that the Tokyo guidelines required revision of the severity grade criteria depending on the results.