Abstract
A 53-year-old woman complained of abdominal pain a week after her first treatment with leuprolide acetate for the bleeding caused by a uterine leiomyoma. CT showed portal and superior mesenteric vein (SMV) thrombosis. She was treated with thrombolytic therapy, but femoral vein thrombosis occurred around the central vein catheter. We undertook inferior vena cava filter placement and operated for bowel obstruction. Pathological examination revealed the obstruction had been caused by SMV thrombosis. It was considered that luprolide acetate might have been associated with the thrombosis because none of the other thrombotic factors was detected.
