Clinical Features and Prognostic Factors in 35 Consecutive Patients Who Underwent Open Abdominal Management Using the ABTHERA^Ⓡ Negative Pressure Wound Healing System

Abstract

Background: The ABTHERA dressing kit for OAM was introduced in Japan in March 2019. However, the actual status of OAM using ABTHERA in Japan is still not clear, and factors affecting the prognosis of patients receiving this treatment remain unknown. Purpose: The purpose of this study was to analyze the clinical features and treatment outcomes and to identify factors related to the short-term survival of patients receiving OAM with ABTHERA. Methods: This study included 35 consecutive OAM patients managed with ABTHERA between June 2019 and June 2021. We divided the patients into trauma and non-trauma groups, and survivor and non-survivor groups. The patient demographic data, including the APACHE Ⅱ scores, were analyzed. Results: Two of 12 patients (16.7％) in the trauma group died, and 10/23 patients (43.5％) in the non-trauma group died. Primary fascial closure was achieved in 32/35 (91.4％) patients. The mean APACHE Ⅱ score was 19.7. The APACHE Ⅱ score was significantly higher in the non-trauma and non-survivor groups. Analysis showed that the APACHE Ⅱ score was associated with the short-term survival. Conclusion: The findings of the present study suggest that determination of the APACHE Ⅱ score is useful for predicting the short-term prognosis of patients with OAM treated with ABTHERA as part of damage control surgery.