2023 Volume 43 Issue 5 Pages 803-808
The present study was conducted to examine the clinical usefulness, problems, and indications of antibiotic administration as the first-line treatment for acute appendicitis. We conducted a retrospective analysis of the clinical data of 60 patients who had undergone conservative treatment for acute appendicitis. Patients were divided into two groups: 49 patients in whom conservative therapy was effective and 11 patients in whom it was not. All patients in the latter underwent emergency appendectomy, and we compared the clinical outcomes between the groups. There were significant differences between the two groups in the incidence of complicated appendicitis, coprolites, ascites, elevated serum C-reactive protein concentrations, and elevated white blood cell counts. In acute appendicitis patients with elevated white blood cell counts and serum C-reactive protein concentrations after conservative treatment, change of the treatment strategy from conservative treatment to surgical treatment should be considered.
