Japanese Journal of Forensic Science and Technology
Online ISSN : 1881-4689
Print ISSN : 1880-1323
ISSN-L : 1880-1323
Case Report
Quantification of Blood Histamine and Tryptase in Fatal Case Suspected to Anaphylactic Shock.
Kouichiro TsugeYasuo Seto
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2007 Volume 12 Issue 2 Pages 231-236

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Abstract
  We report on two forensic cases suspected in connection with anaphylactic shock. Both the patients died just after an anesthetic administration during the operation. The blood histamine and tryptase concentrations of the victims were measured by GC-MS after ethylchloroformyl derivatization and fluoroimmunoassay, respectively. In the first case, the histamine and tryptase concentrations were 58 μg/ml and 25 ng/ml, respectively, were both significantly higher than the normal blood levels. In the second case, neither concentration exceeded the normal level.
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© 2007 Japanese Association of Forensic Science and Technology
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