Calc-silicate rocks develop at the lithological boundaries between khondalite and dolomitic marble (Yoshida et al., 1976; Matsueda et al., 1983) in the Skallevikshalsen, Lützow-Holm Complex, East Antarctica. These calc-silicate rocks also occur as discordant dykes in the khondalite layer. Khondalite progressively changes to Grt-Spl-Bt gneiss (GSB), Grt-Opx-Bt gneiss (GO) and charnockite (CH) toward the calc-silicate dykes. Based on the Isocon analysis (Grant, 1986) of the GS-CH, we consider that (1) partial melting and subsequent melt-segregation occured in the GSB, triggered off by the infiltration of the H2O-rich fluids from the calc-silicate dykes, (2) GO were formed by the mixing of GS and calc-silicate dykes (or melt), (3) CH were formed by the mixing of granitic melt and calc-silicate dykes.