2017 Volume 8 Issue 1 Pages 23-29
ABSTRACT: The aim of this study was to examine whether exercise therapy affected flow-mediated dilation (FMD) in the brachial artery differently in patients with type 2 diabetes mellitus (T2DM) and those with lifestyle-related diseases other than diabetes. The diabetes and non-diabetes groups included eight participants in each group. Aerobic exercises were performed at least twice a week for 40 minutes per session. All parameters were measured at the beginning and after 6 months of exercise therapy. FMD in the diabetes group was significantly improved by exercise therapy. In contrast, there was no significant increase in FMD in the non-diabetes group. The diabetes group did not show any significant reductions in waist circumference, body mass index (BMI), or HbA1c level, while waist circumference and BMI in the non-diabetes group were significantly reduced after exercise therapy. Our results demonstrated that endothelial dysfunction in T2DM was improved by exercise therapy, independent of weight-loss or glycemic control.
