Relationship among hippocampal atrophy, brain blood flow, and neuropsychological tests in patients who experienced forgetfulness

Abstract

The purpose of this study was to apply the stepwise method of discriminant analysis to investigate the relationship among hippocampal atrophy, brain blood flow, and neuropsychological tests in patients who experienced forgetfulness. The neuropsychological tests that presented a relationship with hippocampal atrophy were Revised Hasegawa Dementia Scale and Logical memory Ⅱ. Likewise, the test that presented a relationship with the brain blood flow was Frontal Assessment Battery. These results suggest that Revised Hasegawa Dementia Scale, Logical memory Ⅱ, and Frontal Assessment Battery are useful neuropsychological tests to predict the possibility of hippocampal atrophy and decrease in brain blood flow of precuneus and posterior cingulate gyri.