Abstract
We experienced a rare case of amoebic liver abscess, the infection route of which could not be determined. A 39-year-old man was admitted to our hospital because of a continuous high fever of 38˚C. Abdominal computed tomography (CT) showed a 32 × 38 mm cystic lesion in the right hepatic lobe. We detected the amoeba trophozoite, which ingested red blood cells and showed active amoeboid motion with pseudopodia, in the aspiration of the liver abscess. The serum anti-Entamoeba histolytica IgG level was 100-fold higher than that of normal serum. PCR analysis of the aspiration specimen revealed E. histolytica infection. The patient was treated with percutaneous transhepatic abscess drainage and metronidazole. He had not traveled in endemic areas for about ten years and is not a homosexual. It is highly possible that the infection of this patient is of unknown origin in this country.