Abstract
The number of end-stage kidney disease patients in Japan has exceeded 300,000, and a large amount of money is spent for dialysis. To solve these important problems, it is necessary to determine renal damage at an early stage. In this study, we used CLINITEK Novus provided by Siemens Healthcare Diagnostics, and examined the correlation between albumin and creatinine in urine detected by a dipstick method and a quantitative method. Simultaneously, we analyzed the albumin/creatinine (A/C) ratio, and then evaluated the usefulness of these findings using the renal function parameter (estimated eGFR) and chronic kidney disease (CKD) risk stratification. The results of the dipstick and quantitative methods showed good correlation, and the coincidence rates were 85.9% for albumin and 65.7% for creatinine. Moreover, the A/C ratio determined using these values also showed a good coincidence rate of 85.9% for the dipstick and quantitative methods. The A/C ratio was positive in more than 74.6% of the patients with renal dysfunction. These findings suggest that the dipstick method has potential usefulness for rapid screening.
