Abstract
In this report, we present a basic investigation of the “LATEX H-FABP KIT (YAMASA)” using an all-purpose automated biochemical analyzer. The results indicated that the variation coefficients for simultaneous reproducibility and different-day reproducibility were 0.7–1.8% and 2.2–4.4%, respectively. Moreover, a favorable dilution linearity passing through the origin up to a concentration of 160 ng/mL was obtained. Although no effects of coexistent substances were observed, a clear prozone phenomenon was observed, and the correlation coefficient obtained using the present kit was lower than those obtained using chemical reagents from other companies. The reference range was set at ≤2.0 ng/mL. On the basis of the observation of changes over time with other myocardial markers, it was suggested that it could also be useful for the diagnosis of early acute coronary syndrome and follow-up after reperfusion. We consider, therefore, that although false low values must be avoided with the prozone check setting in highly concentrated serum, the basic performance of this kit is satisfactory and thus it is useful for routine tests.
