Japanese Journal of Medical Technology
Online ISSN : 2188-5346
Print ISSN : 0915-8669
ISSN-L : 0915-8669
Case Reports
Two cases of pancreatic neuroendocrine tumor and gastric gastrointestinal tumor diagnosed by endoscopic ultrasonography fine needle aspiration with cell block procedure
Shiori NISHIKAWATakako TOKUMITSUHiroshi NOGUCHIEiteru KUROKIAkinobu OHNOMasahiro KAIYuichiro SATO
Author information
JOURNALS FREE ACCESS

2015 Volume 64 Issue 5 Pages 559-563

Details
Abstract

Endoscopic ultrasonography fine needle aspiration (EUS-FNA) cytology has proven to be useful for the evaluation of pancreatic tumors or gastric submucosal tumors. In the present study, utilizing the cell block procedure, we examined a diagnostic approach of endoscopic ultrasonography fine needle aspiration (EUS-FNA) cytology in two patients with these lesions. In patient 1, EUS-FNA cytology showed round cells in loose small clumps with focal rosettes or a ribbonlike structure. Immunohistostaining by the cell block procedure revealed the positivity for chromogranin A and synaptophysin in the tumor cells. We diagnosed a neuroendocrine tumor. In patient 2, EUS-FNA cytology showed spindle tumor cells with nuclear palisading. Immunohistostaining by the cell block procedure revealed the positivity for DOG-1, c-kit, and CD34 in the tumor cells. We diagnosed a gastrointestinal stromal tumor. Our findings suggest that EUS-FNA cytology with the cell block procedure offers diagnostic efficacy in patients with pancreatic tumors or gastrointestinal submucosal tumors.

Information related to the author
© 2015 Japanese Association of Medical Technologists
Previous article Next article
feedback
Top