2016 Volume 65 Issue 1 Pages 84-90
Blood hemoglobin A1c (HbA1c) level is widely used as an important parameter for the medical care of diabetes patients. We evaluated the measurement performance of a new HbA1c analyzer based on high-performance liquid chromatography (HPLC: HLC-723 G11, Toso Co., Ltd.). Within-run and day-to-day-run reproducibilities were 0.00 to 0.01% and 0.70 to 0.84%, respectively, in coefficient of variation. Correlation with DM-JACK II was y = 1.043x − 0.23, r = 0.990. There was no interference when adding substances such as bilirubin C and F and chyle. Extremely high concentrations of modified hemoglobin caused interference. In conclusion, the HbA1c measurement performance of HLC-723 G11 has been proven satisfactory as it rapidly provides reliable results for the daily care of diabetes patients.
