2016 Volume 65 Issue 4 Pages 392-398
Intra-abdominal masses are histologically diagnosed by biopsy to differentiate among primary malignant and metastatic tumors, malignant lymphoma, and reactive lesions. In this study, to investigate the usefulness of rapid on-site cytologic evaluation (ROSE), the diagnoses of needle biopsy specimens of intra-abdominal masses were compared between cytological and histological examinations of 69 patients in whom ROSE was performed at the time of needle biopsy. The accuracy of the rapid cytodiagnosis based on the histological diagnosis was 91.3%, which is satisfactory. In 15 of 31 patients for whom malignant lymphoma was included in differentiation by ROSE, a portion of the needle biopsy specimen collected on the same day was subjected to flow cytometry to investigate the immunological phenotype, and analyzable results were obtained in 14 patients. Evaluation of cells of intra-abdominal masses by the combination of needle biopsy and ROSE not only enables the evaluation of the collected tissue but also may also provide indications for the need for additional examinations, which may facilitate a highly accurate diagnosis.
