Abstract
The endometrial cytological findings of TACAS methods and conventional methods are compared. A split sample method was used. Thirty-one endometrial material samples each were prepared by the conventional and TACAS methods. The results are as follows: (1) In terms of preparation background, the TACAS method showed a significantly cleaner background than the conventional preparation method, and the masking of endometrial cells was significantly minimal. (2) In terms of the number of cells, the TACAS method showed a larger number than the conventional preparation method, but the difference was not statistically significant. (3) In comparison with the conventional preparation method, the TACAS method showed a significantly higher or the same frequency of average cell clumps. (4) In terms of the number of cell clumps with long axes, the TACAS method showed a significantly smaller number than the conventional preparation method. (5) The frequency of cell clumps with axes longer than 301 μm is lower in the TACAS method than in the conventional preparation method, but this difference was not statistically significant. (6) The nuclear brightness in the TACAS method is significantly lower than that in the conventional preparation method. From the above-mentioned results, the following became obvious. (1) The detailed observation of nuclei in overlapping cells is necessary because the TACAS method results in deeply stained nuclei compared with the conventional preparation method. (2) However, the preparation with a clean background and without the masking of endometrial cells can be carried out. (3) The preparation of sufficient number and size of cell clumps that are smeared can also be carried out. (4) Therefore, it is expected that the application of the TACAS method in endometrial cytological diagnosis leads to the improvement of diagnostic precision.
