2021 Volume 70 Issue 1 Pages 138-143
A woman in her 40s was treated for deep vein thrombosis and pulmonary artery thrombosis in our hospital. Ultrasound sonography (US) was carried out to examine her lower limb veins owing to a marked increase in her D-dimer level, which revealed that her deep vein thrombosis had worsened. US examination of the pelvic cavity indicated that her ovaries were swollen with a mixture of solid and cystic components, which indicated ovarian cancer. Examinations of both contrast-enhanced computed tomography and magnetic resonance images revealed that the endometrium was irregularly thick, and she was also suspected of having endometrial cancer. On the basis of the above findings, total hysterectomy and bilateral ovariectomy were performed. The pathological diagnosis of these tumors was endometrial adenocarcinoma of the uterus and bilateral ovaries. Thromboembolism is known to occur at a high rate in malignant tumors. In this case report, US examination showed that her deep vein thrombosis in the lower limbs was exacerbated owing to high D-dimer levels, followed by the development of ovarian cancer, which was considered the underlying disease. This case showed that in young to middle-aged women with recurrent deep vein thrombosis, it is necessary to determine whether malignancy is present.