2024 Volume 73 Issue 1 Pages 154-160
Cases of ceftriaxone-related urinary crystals or urolithiasis in children have been reported; however, there is little information about urolithiasis in adult patients. We herein report an adult case of crystalluria that was observed during the administration of ceftriaxone. The patient was a woman in her 90s. During the administration of ceftriaxone at 2 g/day for the treatment of cellulitis in the left lower extremity, reduction in urine output and floating matter (sludge) in urine were recognized. Urinary sediment examination revealed numerous yellow-brown needle-shaped, agglomerated, and irregular plate-like crystals. Acute renal injury due to ceftriaxone-related crystals was suspected on the basis of her clinical course. Sharing of information and cooperation with the pharmacist led to the early discontinuation of the drug and the rapid recovery of renal function.
