2014 Volume 45 Issue 4 Pages 278-281
SPECT-MRI thallium olfacto-scintigraphy (SMT olfactoscintigraphy) with nasal administration of thallium-201 (201Tl) has been developed to determine the lesion of post-traumatic olfactory nerve damage. Disconnectivity of olfactory nerve assessed with SMT olfactoscintigraphy was significantly correlated with the reduced olfactory bulb volume. The migration of nasally administered 201Tl to the olfactory bulb was also significantly correlated with the olfactory bulb weight in the mice. The clinical outcome of the treatment with Kampo medicine in the patients with post-traumatic olfactory impairments was shown.
