2023 Volume 46 Issue 2 Pages 3-8
From October 2000 to March 2021, we examined the clinical features of 349 outpatients with SHS, MCS and EHS (16 years and older) who initially visited our hospital with symptoms. A diagnosis of MCS was made based on the “1999 Consensus”. The average age of the subjects was 47.6 +/-13.3 years, with a male to female ratio of 1:4.82. However, the male-to-female ratio of 34 children aged 15 years or younger was 1:1.15 (p<0.001). A review by disease type indicates that SHS accounted for 22.3% of the cases, decreasing after 2007, with 69.2% thereof progressing to MCS or MCS+EHS. The trend shows that EHS associated with MCS has been on the rise since 2011. There was a significant difference in the male-female ratio between adults and children. The results also suggest that there more females than men develop the disease at an older age. There is a concern that MCS and EHS will increase going forward, so some form of countermeasure is desired.
