The Histomorphologic Evaluation of Humane Maxillary Sinus Floor Augmentation After Four Months Using Tissue Engineering Procedure (CHA, PRP and Somatic Stem Cell Mixing Transplantation)

Abstract

On the maxillary sinus floor augmentation (the maxillary sinus lift) of the basal bone with 1 to 2mm height and poor bone volume, it may not be securable the efficient regenerated bone for poor blood flow from the sinus mucosa membrane and the bed bone, even if applying crushed autogenously bone.
In the range that we could perform as a clinician, the operation of maxillary sinus lift, using three elements of APC-PRP (Auto Platelet concentration Platelet Rich Plasma) as the growth factor, the mixing CHA (carbonate apatite) and the crushed autogenously bone as scaffold, and the somatic stem cell from the ileum which were based on the doctrine of tissue engineering.On 4 months later, when we inserted in the oral implant, an internal diameter used hollow drill of 2 or 3mm, and D2 degree was able to obtain the augmented neonatal bone with the form of block.We performed the histomorphometry examination using the blocked bone.In part |5 that required the most bone augmentation, the ripening ossification rate was 40.15%, the neogenesis ossification rate was 6.40%, and the bone occupancy was 46.75% or more on the mineralization.In bone marrow equivalency region, there is little vascular system between some remained CHA and the bone.The some part of CHA absorbed by the osteoclast-like cell and the osteoblast-like alpha cell were arranged in an orderly manner at the circumference.It passes after setting superstructure of implant in 15 months, and then the prognosis is good.
From the above mentioned, We considered about the collagen type 1, the intercalary potential of Ca²⁺, CO₃^2-, PO₄^3- as the crystal formation, the adjustment of pH by CHA, and the control of bone revelation protein.