Abstract
We evaluated the influences of the component ions (Ag, Au, Cu, In, Ni, Pd, Ti, and Zn) of dental alloys on the in vitro capillary formation of new blood vessels using a human angiogenesis kit (Kurabo). The percent area of new capillary in the presence of Zn ions was the highest, being 106.1% of that in the control group. The percent area decreased in the order of Ag, In, Ti, Ni, Cu, Pd, Au and Zn ions. The new capillary length was also the greatest for Zn ions and the smallest for Ag ions, but the order of the other types of metal ions differed from that of the percent area. Based on these results, if the release of a small amount of Zn ions can be controlled, the active rate of capillary formation may increase, resulting in earlier tissue regeneration.
