RADIOTHERAPY PERFORMED ON FIVE CASES OF RECTAL AND ANAL MALT LYMPHOMA —STUDY OF MULTICENTER (OKAYAMA CONFERENCE OF RADIATION ONCOLOGY: OCRO GROUP) CASES—

Abstract

Rectal mucosa associated with lymphoid tissure (MALT) lymphoma is mainly treated by operation, endoscopic mucosal resection (EMR) and eradication of Helicobactor pylori (H. pylori), while only few cases are treated by radiotherapy. The OCRO (Okayama Conference of Radiation Oncology) group performed radiotherapy on five cases of rectal and anal MALT lymphoma performed radiotherapy. This is our report on these five cases with prognosis.
Five cases are all female and stage IEA (Ann Arbor staging classification). Four had been are treated by other therapeutic procedure (eradication etc.) before radiotherapy.
Radiotherapy was performed 30–36 Gy (total dose) with slightly extended small pelvic field without one case (extended local field). No severe adverse effects were experienced.
Three cases of rectal pure MALT lymphoma of stage I survived over five years without recurrence. If eradication of H. pylori is not effective to rectal MALT lymphoma of stage I, our study suggests radiotherapy is one of the good therapeutic procedures for rectal (and anal) MALT lymphoma.