POSTOPERATIVE RADIATION THERAPY FOR TWO BREAST CANCER PATIENTS WITH AUTOIMMUNE BULLOUS DISEASE

Abstract

The current literature reports that radiation therapy for patients with autoimmune bullous disease due to adverse or aggravating effects is contraindicated. We recently used postoperative radiation therapy to treat breast cancer patients with autoimmune bullous disease. We were initially hesitant to indicate radiation therapy for these patients, but they expressed the earnest wish to preserve their breasts, so we obtained full informed consent, administered reduced-dosage radiation, and increased the amount of regular steroids. Neither severe acute adverse effects nor exacerbation or induction of cutaneous reactions during the radiation therapy was observed, and no severe delayed reactions have been noted to the present.