Abstract
We retrospectively studied 97 patients with stage III-IV cervical cancer treated by radical radiotherapy to clarify the radiotherapeutic parameters that influenced pelvic recurrence. The diseases were staged as III in 75 patients and IV in 22. The patients were treated by whole pelvis irradiation and split field irradiation to the parametrial tissue followed by high dose-rate intracavitary irradiation. The actuarial 5-year pelvic recurrence rate was 27%. Multivariate analyses by the proportional hazard method showed significant positive correlations between pelvic recurrence and the duration of external irradiation, or the total duration of both the external and intracavitary irradiation. The other radiotherapeutic parameters were not related to pelvic recurrence. There was a marked inverse correlation between patient age and pelvic recurrence. T-stage was also a pretreatment factor affecting pelvic recurrence.
