Abstract
Korean Red Ginseng (KRG) has been known to have hypolipidemic effect or insulin like effects on blood sugar and lipid metabolism. Effect of KRG on lipoprotein metabolism were examined in 6 healthy volunteers, who were administerd 1400Cal of diet (fat: 101.8g, carbohydrate: 106.9g, protein: 34.6g) with KRG (3.0g) or placebo after 12hrs fasting.
Lipoproteins were analysed by ultracentrifugation method. Total triglyceride concentration in blood was almost linearily increased for 3hrs up to 200% comparing with the values before diet load. Triglyceride levels in KRG administered groups were slightly less than that of control diet administered groups. Triglyceride in chylomicron and VLDL, and FFA in blood was less in KRG administered group than that of control. Furthermore, HDL cholesterol concentration was not changed. These results suggest that lipid lowering effect of KRG might not be due to the increase in catabolism of triglyceride but to the inhibition of absorption in intestine.
