The Journal of Japan Atherosclerosis Society
Online ISSN : 2185-8284
Print ISSN : 0386-2682
ISSN-L : 0386-2682
The Concentrations of Apolipoprotein A-I and A-II in Hyperlipidemics
Tetsuro SHONOShu-Hwai YENShunichi KOGAHiroshi IBAYASHI
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JOURNAL OPEN ACCESS

1982 Volume 10 Issue 5 Pages 973-976

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Abstract
The concentrations of serum apolipoproteins A-I and A-II were determined in 64 hyperlipidemic subjects by the method of SRID and rocket immunoelectrophoresis. Further determinations were carried out on the levels of apoprotein B (rocket technique), the concentration of triglycerides, total cholesterol and HDL cholesterol.
The concentrations of apo A-I and A-II in the type IV cases were lower than in type II subjects. The A-I and A-II levels were significantly correlated with the levels of HDL cholesterol but not with the levels of triglycerides or total cholesterol.
The concentrations of apo B in the hyperlipidemic subjects were increased markedly and correlated with the levels of total cholesterol but not with the levels of triglycerides.
The concentrations of apo A-I in hyperlipidemic subjects determined by SRID method were correlated with the values obtained by the rocket technique (r=+0.76, n=63), and indicated the validity of the method.
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