The Effects of Plasma Triglyceride on Composition of HDL and LDL in Patients with Ischemic Heart Disease

Abstract

We investigated the effects of plasma triglyceride on the compositions of lipoproteins in 124 male patients with ischemic heart disease (IHD group) and 112 male patients without ischemic heart disease (non IHD group). We found large changes in the core portion of lipoproteins with increasing triglyceridemia. In both groups, the values of log TG has significant positive correlation with that of HDL-TG and LDL-TG and also a negative correlation with that of HDL-TC. In HDL of both groups, the amount of increased TG is equal to that of decreased TC, indicating that these changes of TG and TC are complementary each other. However, the compositions of HDL is 1.3 times more affected by TG in IHD group than non IHD group. These results seem to be useful to consider the atherogenecity of TG.