Effects of Collagens on Human Umbilical Vein Endothelial Cell Growth
1987 Volume 15 Issue 3 Pages 803-804
Details
1987 Volume 15 Issue 3 Pages 803-804
The role of collagens on human umbilical vein endothelial cell (HUV-EC) growth was investigated. Any type of collagens (type I, II, III, IV, V), coated on culture dishes, facilitated to proliferate HUV-EC without any growth factor. HUV-EC proliferated more efficiently on the type I or IV collagen coated dishes with endothelial cell growth supplement (ECGS). The optimum dose of collagens for EC growth was seen (4-40μg/well) and EC growth was inhibited with high dose of collagens (400μg/well) even in the presence of growth factors.
