Serum Sialic Acid Concentration in Diabetic Subjects with Special Reference to Lipid Concentration

Abstract

Serum sialic acid and lipid concentration weremeasured in 17 healthy controls, in 13 hyperlipidemic subjects, and in 42 diabetic subjects. In diabetic subjects there was a significant increase in age, fasting plasma glucose, total cholesterol (TC), triglyceride (TG), and LDL-cholesterol (LDL-ch) as compared with those in healthy controls. But there was no significant difference inserum sialic acid and HDL-cholesterol. In female diabetic subjects a significant positive correlation was observed between sialic acid andTC, TG.
In female diabetic subjects with hyperlipidemia there was significant increase in sialic acid, TC and LDL-ch than healthy controls, hyperlipidemia and diabetic subjects without hyperlipidemia and a significant positive correlation between sialic acid and TG in type IIb hyperlipidemia.
From these observasions we suggest the correlation between sialic acid and lipid concentrasion in diabetic subjects.