A Study on Lipid and Fatty Acid Composition in Aortas, Hearts and Adipose Tissues of Mice Treated with Cigarette Smoke for a Long Term

Abstract

We have analyzed fatty acid composition of the aortas, hearts and adipose tissues of the mice treated with cigarette smoke of long-term inhalation. We have observed two characteristic factors: (I) Linoleic acid percentage in aortic cholesterylester fraction and phospholipid fraction decrease by smoking (2) Arachidonic acid percentage in aortic cholesterylester fraction decrease. These findings mean that smoking brings about an atherosclerogenic condition in the aorta.