Abstract
Serum cholesterol, triglyceride and high density lipoprotein (HDL) cholesterol were measured in 41 consecutive male patients with cineangiogra-phically defined coronary artery disease (CAD). 96 first- and second-degree relatives of 7 patients with type IV hyperlipoproteinemia were also investigated.
The HDL cholesterol was significantly lower in patients and in male relatives of 20-60 years old than in controls, but there was slight decrease in female relatives and children. Serum triglyceride was significantly higher in patients and in male relatives of 20-60 years old than in controls, but there was no increase in other family members. No increase of serum cholesterol was found in patients and relatives.
The results suggest that HDL cholesterol and triglyceride are related not only to genetic factors but also to sex and age factors.
