Abstract
The anatomical features of the kidney in cats can be described as a series assemblies of renal lobules in terms of electrical alignment. Interlobular arteries may become hypoxic and malfunction on a lobular basis. Therefore, the progression of renal dysfunction in cats is faster than that in humans and dogs. Approximately 70% of cats with CKD have no urinary protein leakage. The cause is hypothesized to be a decrease in glomerular filtration pressure by blood circulation failure in the interlobular arteries. Beraprost sodium improves renal blood flow and maintains renal function when renal blood flow is reduced by CKD progression.
