Abstract
Renal biopsy is an essential and indispensable technique for diagnosing kidney diseases, especially glomerular disease which induces protein-losing nephropathy. However, renal biopsy is invasive and should not be performed without careful consideration. In addition, the pathological diagnosis of glomerular disease requires not only general light microscopic observations but also electron microscopic and immunofluorescent analyses, and it requires adequate knowledge for handling the collected kidney tissues. This article describes the anatomy of the kidney and sampling methods, as well as the tissue handling to lead to an appropriate pathological diagnosis.
