2020 Volume 71 Issue 6 Pages 414-420
In esophageal cancer cases, there are many cases involving multiple primary cancers, and treatment is often difficult. Cases of synchronous esophageal and renal cancers are rare, however, and there is no consensus on how to treat them. Here, we report a case of unresectable advanced esophageal cancer, oropharyngeal cancer, and renal cancer which was successfully treated with multidisciplinary treatment. A 66-year-old male was diagnosed with advanced esophageal cancer with tracheal invasion. Further examination also revealed oropharyngeal cancer and left renal cancer. As nephrectomy was considered necessary to treat the renal cancer, chemoradiotherapy including 5-FU and cisplatin was performed first to treat the esophageal cancer. After chemoradiotherapy, the esophageal cancer decreased in size-and might be curable with additional therapies; then left nephrectomy was performed. After additional chemotherapies, salvage surgery was performed for the esophageal cancer. To treat the oropharyngeal cancer, chemotherapy markedly reduced its size and a complete response was achieved by additional radiotherapy. Now, 17 months after the initial treatment, the patient is alive and well without recurrence of any cancers. In patients with synchronous renal cancer, it is necessary to conduct well-balanced multidisciplinary treatment, considering the timing of using cisplatin, a key drug in esophageal or head and neck cancers.
