Abstract
1. A statistical investigation of oesophagitis circumscripta oedematosa chronica in 91 patients is present.
2. As an initial sign of this lesion, congestion or hyperemia of capillaries in submucous layer of the esophagus is histologically observed. Following increased permeability of capillaries serous transudate appears and then edema, hemorrhagia per diapedesin or rhexin and cell infiltration take place.
In the second stage fibrin appears in the edematous, region, and sometimes organization process, varix like formation or change of glandular ducts are demonstrated.
3. Not only these histopathological changes but also the characteristic tendency of patients to worry about cancer, tuberculosis or ascaris in the laryngo-esophageal region are of impotance in the concept of this lesion, as those people with extreme traits of neurosis are liable to manifest severe subjective symptoms.