Clinicopathological Study on Bronchoscopic Instillation of Therapeutic Agents into the Pulmonary Cavity

Abstract

SM and/or INH were bronchoscopically instilled into tuberculous cavities in 98 cases and the progress studied on the efficacy of these treatments.
In 14 cases which did not respond to the bronchoscopic treatment an extirpation of the affected lesion was made and histologic examinations were carried out. The author found that in addittion to cleaned-out cure which he noted in one case, factors which resisted the tretment are cicatricial changes of the lesion, tortuous stenosis of the draining bronchus, and thick pleural adhesions.