1971 Volume 22 Issue 2 Pages 82-89
Endoscopic findings of chronic bronchitis syndrome were classified into five types, and histochemical and electron-microscopic studies were performed in tissues obtained from mucous membrane of the bronchi of these cases. From the intensive study on the mucus producing cells, it was evident that cough and difficulty expectoration followed by difficulty breathing were caused by disorder or dysfunction of the secretory system of goblet cells and grandular cells.