Abstract
1) The correlation between air pollution and respiratory diseases in childhood, especially bronchial asthma, asthmatic bronchitis and chronic bronchitis were investigated. The frequency of the asthmatic bronchitis and bronchitis in air polluted area were increased significantly.
2) As to the pulrnonary function, there was no significant difference between the non-air polluted area and air-polluted area, but there was found the slightly increase of air way resistance by oscillation technique in air polluted area.
3) Histopathological classification of chronic bronchopathy in childhood by bronchial biopsy was performed and was found that the chronic bronchitis was the epithelial cell denudation type. It was speculated that the recurrent air way infection in chronic bronchitis was based upon such histological finding.
4) An electron histochemical study of the adult rat and infant rat lung by NO2 gas inhalation was investigated. The results obtained that the different reactions were demonstrated in type II alveolar cells between adult rat and infant rat.