Abstract
A 61-year-old female was admitted to our hospital complaining of fever and dyspnea. She had been using a humidifier in her home before admission.
A chest X-ray film on admission showed diffuse micronodular shadows in the bilateral lung fields. A transbronchial lung biopsy revealed specific findings of hypersensitivity pneumonitis.
A provocation test using the humidifier was positive, and a diagnosis of humidifier lung was made. The precipitin antibody reaction of the patient's serum to various antigens was negative, but Acremonium and Cladosporium were cultured from water in the humidifier. We therefore speculated that these fungi could be the pathogenic antigens.
However, an inhalative provocation test using these fungi was not performed due to her refusal.