Japanese journal of bone and mineral metabolism
Online ISSN : 1884-9210
Print ISSN : 0910-0067
ISSN-L : 0910-0067
Cartilage-derived Antitumor Factor (CATF)
A High Molecular Weight Fraction in Cartilage Extract Inhibits Solid Tumor Growth
Fujio SUZUKI, Masaharu TAKIGAWA, Yuji HIRAKI, Yukio KATO, Keisuke FUKUO, Tsuyoshi SHIIO, Yasumi YUGARI
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1984 Volume 2 Issue 3 Pages 231-235

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Abstract
A high molecular weight factor(s) was extracted from fetal bovine cartilage with 1M guanidine hydrochloride. This factor inhibited neither the proliferation of sarcoma 180 cells in culture nor the growth of their ascites form. However, it strongly inhibited the growth of solid sarcoma 180 in vivo.
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© The Japanese Society for Bone and Mineral Research
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