2024 Volume 50 Issue 1 Pages 6-11
Background: In this report, we describe pediatric cases of deep dermal burn (DDB) of the foot treated with enzymatic debridement using NexoBrid® and RECELL®. We achieved early and complete epithelialization; however, sedation and analgesia were difficult to manage. Adequate analgesia and sedation are important with regard to the use of NexoBrid®. This study aimed to assess the usefulness of the NexoBrid® and RECELL® combination in pediatric DDB and the problems associated with its management.
Case: We experienced two cases of infants with dorsal foot burns. Case 1 was a 10-month-old boy who was burned by boiling water. Enzymatic debridement was performed under general anesthesia, but the patient had difficulty maintaining postoperative rest and debridement was partially inadequate. RECELL® was performed under general anesthesia on the 11th day after injury. Ten days after RECELL®, total epithelialization was confirmed. Case 2 was a 1-year-old boy who was burned by boiling water. Enzymatic debridement with NexoBrid® was performed under general anesthesia on the 6th day after injury. On the 7th day after the injury, the patient underwent RECELL® under general anesthesia in the ICU. Eight days after RECELL®, total epithelialization was confirmed.
