Japanese Journal of Burn Injuries
Online ISSN : 2435-1571
Print ISSN : 0285-113X
Original
Review of Our 10 Years Experience in Treating Extensive Burns withCultured Epidermal Autografts at Hokkaido University Hospital
Naoki MuraoMasahiro HojoTakahiro MiuraKosuke IshikawaTaku MaedaTakeshi YamaoMunezumi FujitaEmi FunayamaYuhei Yamamoto
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2025 Volume 51 Issue 1 Pages 1-8

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Abstract

 Objectives: More than 10 years have passed since the introduction of cultured epidermal autografts (CEA) for extensive burns in our institution. We investigated the effect of CEA on the prognosis of patients with extensive burns. 
 Methods: We conducted a retrospective analysis of 28 patients who underwent surgery at Hokkaido University Hospital for deep partial-thickness and full-thickness burns covering 30% or more of the body surface area between April 2000 and March 2020. The patient’s age, sex, burned area, burn index (BI), burn prognostic index (PBI), use of CEA, and outcomes were evaluated.
 Results: The burned area, BI, and PBI values of the cases that died after the introduction of CEA were significantly higher than those of the cases that died before its introduction. Significantly more surviving cases were treated with CEA during the entire period.
 Conclusion: In our institution, CEA improved the prognosis of patients with extensive burns.

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© 2025 Japanese Society for Burn Injuries
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