Abstract
We have developed the G-InforBIO for seamless integration of browse and analysis of genomic data. Major functions of the suite are database management, data retrieval, sequence data analysis and the visualization for genomics. An annotation database accommodates multiple flat files (FFs) of entries registered in the International Nucleotide Sequence Database Collaboration (INSDC, DDBJ/EMBL/GenBank) and also tab-delimited files of local data. Genome information on the imported annotation database can be readily retrievable using keyword searches. A subset of nucleotide and protein sequences can be also retrieved for the further analysis and graphical representation. The G-InforBIO includes sequence analysis programs for cluster analysis (BLASTCLUST, ClustalW, and SOM) and homology analysis (MegaBLAST, BLAST, Blat, and Sim4). The analysis can be applied to the retrieved subset and data imported from outside. The system provides a broad-ranging utilization of genome information. The suite is written in Java so that it is executable in Macintosh OSX, Windows XP, Linux, and Unix machines and will be downloadable from http://www.wdcm.org/inforbio/G-InforBIO/download.html. The instruction manual of the G-InforBIO can be browsed at http://www.wdcm.org/inforbio/G-InforBIO/manual_E/index.htm.
