2019 Volume 25 Issue 4 Pages 98-101
Introduction: In Japan, the prevalence of unmarried people is increasing. Sometimes, young men who suffer from acute coronary syndrome (ACS) are unmarried. Few reports discussing age at ACS onset and marital status have been reported. Methods and Results: We analyzed 160 patients who came to our hospital with a diagnosis of ACS between January 2017 and September 2018. We excluded 33 men who were over 75 years old. Among the remaining 99 men who were under the age of 75 years, we compared a married group (MG: n = 66) and a single group (SG: n = 33). The clinical characteristics were examined using t-tests. The age at the onset of ACS was significantly younger in the SG than in the MG (62.6±8.6 vs. 57.3±10.0 years; P = 0.007). The low-density to high-density lipoprotein ratio (L/H) was significantly higher in the SG than in the MG (MG: 2.7±0.9 vs. SG: 3.2±1.3; P= 0.027). Using statin was significantly higher in the MG than in the SG (MG: 18.3%±34.2 vs. SG: 6.0%±40.1; P=0.038). There were no differences in hypertension, low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride, diabetes mellitus, HbA1c, body mass index (BMI), serum creatinine, uric acid and smoking habit between the two groups. There was no difference in the previous percutaneous coronary intervention (PCI), the percentage of ST elevation myocardial infarction (STEMI), peak creatinine kinase-MB (CK-MB), the number of significant fixed stenosis, the percentage of the culprit lesion was LAD (left anterior descending) artery. Multi-variable analysis revealed that marital status was the independent risk factor for young onset of ACS. Conclusion: Single men have a greater risk of early-onset ACS than married men. However, the mechanism for this difference remains unknown, and further studies are required.
