Abstract
Objectives: In an extremely aging society, it is beneficial to precisely predict the prognosis of high-risk late-elderly patients with coronary artery disease (CAD). Therefore, we aimed to investigate the prognostic value of the Geriatric Nutritional Risk Index (GNRI) for major adverse cardiac events (MACE) in elderly patients aged ≥ 75 years.
Materials and methods: This study included 754 consecutive late-elderly patients with CAD who underwent percutaneous coronary intervention (PCI). The patients were prospectively followed up for up to 3 years or until the occurrence of MACE, defined as a composite of all-cause death, non-fatal myocardial infarction, and non-fatal stroke.
Results: During the follow-up period, MACE occurred in 157 patients. Kaplan–Meier analysis showed that the lower the GNRI, the higher the probability of MACE. According to a multivariable logistic analysis with the highest GNRI level as the reference, the lowest GNRI level was related to the highest occurrence of MACE. In the stratified analysis, the lowest GNRI group had an increased risk of MACE, especially those with a female sex, no hemodialysis, a non-smoking status, statin use, no loop diuretics, no acute coronary syndrome, or multivessel disease had an increased risk of MACE, even with only a small reduction in GNRI compared with the highest level.
Conclusion: GNRI can effectively predict the occurrence of MACE in elderly patients after PCI.
