Effects of Oral Administration of CoenzymeQ10 to Nonenal in Skin Gas of Elderly Women

Abstract

To evaluate the impact of coenzyme Q10 (CoQ10) intake on body odor, two studies that focused on 2-nonenal contained in the gases emanated from the skin were conducted. The first study targeted 20 healthy women aged 65–74 years in a placebo-controlled cross-comparison study. Subjects were divided into two groups using blood CoQ10 concentration as an index, with ubiquinol (QH) or placebos administered every 4 weeks (5-week washout). On measuring concentrations of CoQ10 in blood and 2-nonenal in skin gas before and after continuous use, CoQ10 level of QH intake group increased significantly, whereas 2-nonenal level reduced significantly. In the second study, 24 healthy women aged 65–74 years were divided into four groups. QH, ubiquinone, vitamin E and placebos were administered in 4 weeks, and each concentrations of 2-nonenal in skin gas were measured. QH and ubiquinone reduced 2-nonenal in skin gas; however, changes in vitamin E were not observed. Therefore, CoQ10 intake reduced 2-nonenal emanation from the body.